A/Professor Caroline Gorvin
"Caroline is an Associate Professor and Sir Henry Dale Fellow at the University of Birmingham, UK. She obtained her BSc (Hons) in Biomedical Science with Industrial Experience in 2008 from the University of Manchester and spent her year in industry at AstraZeneca plc in the in vitro electrophysiology team. Caroline then moved to the University of Oxford for her PhD studies, where her research focussed on the cellular mechanisms by which mutations in a chloride-proton antiporter cause the renal disorder Dent’s disease. She also spent time on secondment at UMC St Radboud, Nijmegen, The Netherlands, during this period.
Caroline continued in Oxford undertaking postdoctoral research with Professor Raj Thakker’s group investigating the signalling and trafficking of calcium-sensing receptor (CaSR), and its role in calcium homeostasis. Her research has: defined new paradigms for CaSR signalling by spatiotemporal G-protein pathways; described new disease-biased CaSR signalling pathways; repurposed allosteric modulators for patients with hyper/hypocalcaemia; and contributed to informing clinical guidelines for genetic testing in hypercalcaemia.
She moved to the University of Birmingham in January 2018 to establish her research group where she continues to work on CaSR signalling alongside research programmes investigating GPCRs involved in appetite regulation."